Hi,
After Infecting Virus in ur Computer. The drives can't be opened by double clicking,or 'Open', U need to delete Autorun.inf files in Every drive (in Root of every drive), & also delete some keys in the registry, But if u have a good idea on Regedit u can do it,( I Recommend to take back up of registry before).

Or U can use good antivirus like Mcafee , symantec etc , with latest updates...