Active Directory & IIS Permissions

[origenes]

Hello;

This is the situation:

In PC 1 I have the Active Directory
In PC 2 I have running the IIS and an Intranet.

I want to set different group/users permissions to the intranet. For example I want some users can navigate in intranet/folderX and other not.

What I should do?

Any idea is welcome, happy 2007 to all!

[origenes]

Sorry, I forgot to say that the workstations have windows 2003 installed.

Thank you