changing hyperlinks in code

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On an aspx page I have text that is a Hyperlink to an html page. The text is
not on a button, but is just plain text that has been converted to a
Hyperlink.

Is it possible to specify or change the URL associated with the Hyperlink in
the Page_Load() event (or another type of code handler) before or after the
Hyperlink is clicked.

Thanks for any tips, comments, or information.
--
Gary Larimer